An upright microscope with DIC optics, an alternate high NA darkfield, fluorescence and Photometrics Prime sCMOS camera. The Photometrics Prime is the best camera that we have on the available widefield microscopes, and is excellent for high frame rate timelapses or samples with low intensity fluorescence. This microscope is equipped with a 4, 10, 20, 40X dry objectives and a 100X oil immersion objective with Iris.